Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | FPR2 | P25090 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8644919 | 0.99 | ALDH1A1 (0.31) | KDM1AFPR2 | |
| SCHEMBL8640119 | 0.99 | ALDH1A1 (0.31) | KDM1AFPR2 | |
| SCHEMBL8638542 | 0.96 | KDM1A (0.32) | KDM1AFPR2L3MBTL1 | |
| SCHEMBL8640332 | 0.91 | KDM1A (0.33) | KDM1AFPR2 | |
| SCHEMBL8635244 | 0.85 | KDM1A (0.35) | KDM1AFPR2L3MBTL1 | |
| SCHEMBL9571143 | 0.85 | THRB (0.32) | — | |
| SCHEMBL9571157 | 0.84 | THRB (0.34) | — | |
| SCHEMBL9571094 | 0.84 | THRB (0.34) | — | |
| SCHEMBL9571158 | 0.81 | HTR2C (0.31) | — | |
| SCHEMBL8636467 | 0.81 | CYP1A2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440082-B1 | Method for the conversion of fluorinated aromatic compounds using electrophiles | MERCK PATENT GMBH (DE) | 1998-04-15 | — | — | EP | disclosed |
| US-5262556-A | Alkylation or hydroxyalkylation by deprotonation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-11-16 | — | — | US | disclosed |
| EP-0440082-A2 | Method for the conversion of fluorinated aromatic compounds using electrophiles | MERCK PATENT GmbH (DE) | 1991-08-07 | — | — | EP | disclosed |