Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KLK7 | P49862 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | PAM | P19021 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641583 | 0.90 | PTGS2 (0.37) | TSHRLMNAKLK7MAPK1KMT2A | |
| SCHEMBL8646191 | 0.88 | TSHR (0.36) | TSHRLMNAKLK7MAPK1KMT2A | |
| SCHEMBL8644037 | 0.86 | TSHR (0.40) | TSHRLMNAKLK7MAPK1KMT2A | |
| SCHEMBL8646856 | 0.86 | PTGS1 (0.41) | TSHRLMNAKLK7MAPK1KMT2A | |
| SCHEMBL8642449 | 0.85 | TSHR (0.39) | TSHRLMNAKLK7MAPK1KMT2A | |
| SCHEMBL10952749 | 0.81 | ALDH1A1 (0.50) | TSHRLMNAKLK7MAPK1KMT2A | |
| SCHEMBL2906104 | 0.78 | TSHR (0.49) | TSHRLMNAKLK7MAPK1KMT2A | |
| SCHEMBL8646827 | 0.76 | KLK7 (0.38) | TSHRLMNAKLK7KMT2AHTT | |
| SCHEMBL28770289 | 0.76 | TSHR (0.45) | TSHRLMNAKLK7MAPK1KMT2A | |
| SCHEMBL10615027 | 0.74 | CLCN2 (0.39) | TSHRLMNAKLK7MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5844696-A | Nitric esters from derivatives of 2-(2,6-dihalophenylamino) phenylacetoxyacetic acid and their preparation process | PRODES, S.A. (ES) | 1998-12-01 | — | — | US | disclosed |
| EP-0738706-B1 | Nitric esters of 2-(2,6-dihalophenylamino) phenylacetoxyacetic acid derivatives and their preparation process | PRODES SA (ES) | 1998-10-07 | — | — | EP | disclosed |
| EP-0738706-A1 | Nitric esters of 2-(2,6-dihalophenylamino) phenylacetoxyacetic acid derivatives and their preparation process | PRODES, S.A. (ES) | 1996-10-23 | — | — | EP | disclosed |