SCHEMBL8645166

SCHEMBL8645166

CN(C)c1ccc([S+](c2ccc(N(C)C)cc2)c2cccc(OC(C)(C)C)c2)cc1.O=S(=O)([O-])c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8651804 0.90 KAT6A (0.33)
SCHEMBL8647720 0.89 HDAC6 (0.34) HDAC6
SCHEMBL6760271 0.89 KAT6A (0.33)
SCHEMBL8646194 0.89 HDAC6 (0.34) HDAC6
SCHEMBL8320963 0.88 ALDH1A1 (0.31)
SCHEMBL8316998 0.88 ALDH1A1 (0.31)
SCHEMBL8645334 0.85 PSEN1 (0.36) HDAC6
SCHEMBL8317929 0.84 ALDH1A1 (0.33)
SCHEMBL8322099 0.84 ALDH1A1 (0.33)
SCHEMBL8647792 0.83 GRM2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5824824-A AROMATIC SULFONATE ANIONS AND DISSOLUTION CONTRAST IN EXPOSED AND NONEXPOSED AREAS, POSITIVE RESISTS SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-10-20 US disclosed