SCHEMBL6760271

SCHEMBL6760271

CC(C)(C)Oc1cccc([S+](c2ccccc2)c2ccccc2)c1.O=S(=O)([O-])c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 4/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA13 Q8N1Q1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8651804 0.96 KAT6A (0.33) KAT6A
SCHEMBL3206280 0.91 CA12 (0.31) CA12CA1CA2CA7CA13
SCHEMBL8645166 0.89 HDAC6 (0.31)
SCHEMBL2903712 0.89 CA12 (0.32) CA12CA1CA2CA7CA13
SCHEMBL8083692 0.89 CA12 (0.32) CA12CA1CA2CA7CA13
SCHEMBL8644644 0.86 FFAR1 (0.37)
SCHEMBL3136018 0.86 TSHR (0.40) KAT6A
SCHEMBL8643877 0.85 ELANE (0.36) KAT6ACA2
Trifluoromethanesulfonic Acid SCHEMBL6762567 0.85 GPR3 (0.35) KAT6A
SCHEMBL3195811 0.84 SLC6A9 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6723483-B1 Sulfonium salt compounds WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2004-04-20 US disclosed
EP-1113005-B1 Sulfonium salt compounds WAKO PURE CHEM IND LTD (JP) 2003-08-06 EP disclosed
EP-1238969-A2 Sulfonium salt compounds Wako Pure Chemical Industries, Ltd. (JP) 2002-09-11 EP disclosed
EP-1113005-A1 Sulfonium salt compounds Wako Pure Chemical Industries, Ltd. (JP) 2001-07-04 EP disclosed
US-5824824-A AROMATIC SULFONATE ANIONS AND DISSOLUTION CONTRAST IN EXPOSED AND NONEXPOSED AREAS, POSITIVE RESISTS SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-10-20 US disclosed