Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 4/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28627881 | 1.00 | DNM1 (0.71) | DNM1ALDH1A1TSHRTHRBTHRA | |
| Sulfuric Acid SCHEMBL895681 | 1.00 | DNM1 (0.71) | DNM1ALDH1A1TSHRTHRBTHRA | |
| Sulfuric Acid SCHEMBL9117833 | 1.00 | DNM1 (0.71) | DNM1ALDH1A1TSHRTHRBTHRA | |
| Sulfuric Acid SCHEMBL11643413 | 1.00 | DNM1 (0.71) | DNM1ALDH1A1TSHRTHRBTHRA | |
| Sulfuric Acid SCHEMBL6684700 | 1.00 | DNM1 (0.71) | DNM1ALDH1A1TSHRTHRBTHRA | |
| Sulfuric Acid SCHEMBL9117820 | 1.00 | DNM1 (0.71) | DNM1ALDH1A1TSHRTHRBTHRA | |
| Sulfuric Acid SCHEMBL23248613 | 1.00 | DNM1 (0.71) | DNM1ALDH1A1TSHRTHRBTHRA | |
| Sulfuric Acid SCHEMBL17743602 | 1.00 | DNM1 (0.71) | DNM1ALDH1A1TSHRTHRBTHRA | |
| Sulfuric Acid SCHEMBL10609910 | 1.00 | DNM1 (0.71) | DNM1ALDH1A1TSHRTHRBTHRA | |
| Octane SCHEMBL29166416 | 1.00 | DNM1 (0.71) | DNM1ALDH1A1TSHRTHRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723342-A | MEASUREMENT OF ELECTROLUMINESCENCE OF SOLUTIONS AND DETECTION | BOEHRINGER MANNHEIM GMBH (DE) | 1998-03-03 | — | — | US | disclosed |
| US-5677192-A | USING AN OXIDIZABLE AMINE SOLUTION CONTAINING A DETERGENT | BOEHRINGER MANNHEIM GMBH (DE) | 1997-10-14 | — | — | US | disclosed |
| EP-0233385-A1 | Method for detecting a member of a ligand-receptor pair, method for the preparation of a carrier to which this member is bonded and analysis equipment therefor | DE STAAT DER NEDERLANDEN VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGEZONDHEID EN CULTUUR (NL) | 1987-08-26 | — | — | EP | disclosed |