Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642886 | 0.85 | ITGB3 (0.41) | ITGB3ITGA2BSLC9A1TDP1MC4R | |
| SCHEMBL8645365 | 0.83 | TDP1 (0.43) | ITGB3ITGA2BSLC9A1TDP1POLB | |
| SCHEMBL8644236 | 0.81 | SLC6A3 (0.49) | SIGMAR1HRH3ALDH1A1 | |
| SCHEMBL8647542 | 0.81 | MC4R (0.36) | ITGB3ITGA2BSLC9A1TDP1MC4R | |
| SCHEMBL8645350 | 0.81 | ITGB3 (0.50) | ITGB3ITGA2BSLC9A1F2MEN1 | |
| SCHEMBL8647892 | 0.77 | SMN1; SMN2 (0.57) | ITGB3ITGA2BMEN1KMT2AHRH3 | |
| SCHEMBL8642889 | 0.77 | HTT (0.41) | ITGB3ITGA2BSLC9A1TDP1MC4R | |
| SCHEMBL4434863 | 0.74 | ITGB3 (0.71) | ITGB3ITGA2B | |
| SCHEMBL8649064 | 0.74 | ITGB3 (0.71) | ITGB3ITGA2B | |
| SCHEMBL5144245 | 0.74 | ITGB3 (0.71) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726185-A | BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELET AGGREGATION AND CELL TO CELL ADHESION | HOFFMANN-LA ROCHE INC. (US) | 1998-03-10 | — | — | US | disclosed |