Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.39 |
| ▸ | CETP | P11597 | 2/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8647880 | 1.00 | PTGES2 (0.39) | PTGES2CETPKAT6AHDAC3HDAC4 | |
| SCHEMBL8646470 | 0.96 | HDAC3 (0.37) | PTGES2CETPKAT6AHDAC3HDAC4 | |
| SCHEMBL8644626 | 0.89 | GRM2 (0.33) | PTGES2CETPHDAC3HDAC4HDAC1 | |
| SCHEMBL8647797 | 0.89 | GRM2 (0.33) | PTGES2CETPHDAC3HDAC4HDAC1 | |
| SCHEMBL8651818 | 0.88 | HSD11B1 (0.38) | ALDH1A1CYP3A4CYP2C19ABCC9ABCC8 | |
| SCHEMBL8646731 | 0.88 | HSD11B1 (0.38) | ALDH1A1CYP3A4CYP2C19ABCC9ABCC8 | |
| SCHEMBL8317619 | 0.87 | PTGES2 (0.37) | PTGES2KAT6ATAS2R14HSD11B1PGR | |
| SCHEMBL8651442 | 0.84 | RORA (0.35) | PTGES2CETPALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL8646164 | 0.84 | CYP3A4 (0.39) | KAT6AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8648382 | 0.84 | CYP3A4 (0.39) | KAT6AHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824824-A | AROMATIC SULFONATE ANIONS AND DISSOLUTION CONTRAST IN EXPOSED AND NONEXPOSED AREAS, POSITIVE RESISTS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |