Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 10/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 10/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050378 | 0.88 | ACACB (0.49) | ACACBTRPV4CYP11B1CYP11B2MAOA | |
| SCHEMBL56634 | 0.86 | TRPV4 (0.57) | TRPV4CYP11B1CYP11B2MAOAMAOB | |
| SCHEMBL9612005 | 0.84 | TRPV4 (0.55) | TRPV4CYP11B1CYP11B2 | |
| SCHEMBL27214759 | 0.82 | ACACB (0.46) | ACACBTRPV4CYP11B1CYP11B2FFAR1 | |
| SCHEMBL22109247 | 0.78 | ACACB (0.49) | ACACBFFAR1FFAR4GRM5NR3C2 | |
| SCHEMBL5139851 | 0.77 | FFAR1 (0.51) | ACACBFFAR1FFAR4GRM5HAO1 | |
| SCHEMBL22225479 | 0.77 | TRPV4 (0.48) | TRPV4CYP11B1CYP11B2FFAR1FFAR4 | |
| SCHEMBL6864959 | 0.76 | TRPV4 (0.47) | TRPV4CYP11B1CYP11B2FFAR1FFAR4 | |
| SCHEMBL9293782 | 0.76 | CYP11B1 (0.50) | TRPV4CYP11B1CYP11B2FFAR1FFAR4 | |
| SCHEMBL1797379 | 0.76 | TRPV4 (0.59) | TRPV4CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648723-B1 | Diphenylacetylene compound, process for preparing the same and liquid crystal composition and element comprising the same | SUMITOMO CHEMICAL CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5658489-A | EXCELLENT ANISOTROPY OF REFRACTIVE INDEX; LOW VISCOSITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0648723-A1 | Diphenylacetylene compound, process for preparing the same and liquid crystal composition and element comprising the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-04-19 | — | — | EP | disclosed |