Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6547132 | 0.76 | PIK3CD (0.35) | POLBFKBP1AGRM2ACE | |
| SCHEMBL28394560 | 0.76 | CYP2D6 (0.46) | POLBMAPK1TSHR | |
| SCHEMBL2680079 | 0.75 | POLB (0.36) | POLBMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL10077981 | 0.70 | PIK3CD (0.36) | POLBFKBP1A | |
| SCHEMBL10115322 | 0.69 | POLB (0.38) | POLBGRM2MAPK1SMN1; SMN2 | |
| SCHEMBL28392227 | 0.69 | MAPT (0.42) | POLBSMN1; SMN2 | |
| SCHEMBL3414464 | 0.69 | FKBP1A (0.39) | FKBP1A | |
| SCHEMBL11170830 | 0.68 | TSHR (0.50) | MAPK1TSHRSMN1; SMN2 | |
| SCHEMBL1051503 | 0.68 | TSHR (0.50) | MAPK1TSHRSMN1; SMN2 | |
| SCHEMBL873507 | 0.68 | TSHR (0.50) | MAPK1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835251-A1 | PROCESS FOR THE PRODUCTION OF LIPOIC ACID | ASTA Medica Aktiengesellschaft (DE) | 1998-04-15 | — | — | EP | disclosed |