SCHEMBL8645646

SCHEMBL8645646

COC(=O)C(C)(C)C(C)CCCCC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
ALDH1A1 P00352 3/20 0.40
FFAR4 Q5NUL3 1/20 0.40
FFAR1 O14842 1/20 0.40
KDM4C Q9H3R0 2/20 0.38
KDM4A O75164 1/20 0.38
PHF8 Q9UPP1 1/20 0.38
KDM2A Q9Y2K7 1/20 0.38
LMNA P02545 2/20 0.38
GSTK1 Q9Y2Q3 2/20 0.38
PLA2G10 O15496 1/20 0.37
ENPEP Q07075 1/20 0.37
NFKB1 P19838 1/20 0.37
PMP22 Q01453 1/20 0.37
AKR1B1 P15121 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.35
SLC22A8 Q8TCC7 1/20 0.35
GPR84 Q9NQS5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22190520 0.98 ALDH1A1 (0.43) TSHRALDH1A1FFAR4FFAR1KDM4C
SCHEMBL620277 0.95 TSHR (0.42) TSHRALDH1A1FFAR4LMNAGSTK1
SCHEMBL4605980 0.93 TSHR (0.41) TSHRALDH1A1FFAR4FFAR1LMNA
SCHEMBL21580900 0.85 TSHR (0.45) TSHRALDH1A1LMNA
SCHEMBL22573795 0.82 PRSS1 (0.46) LMNA
SCHEMBL32680457 0.82 ALDH1A1 (0.41) TSHRALDH1A1FFAR4FFAR1KDM4C
SCHEMBL7162252 0.82 FFAR4 (0.44) TSHRALDH1A1FFAR4FFAR1LMNA
SCHEMBL7613397 0.81 ZDHHC7 (0.47) FFAR1LMNAGPR84
SCHEMBL18097883 0.81 ZDHHC7 (0.47) FFAR1LMNAGPR84
SCHEMBL5167002 0.81 ZDHHC7 (0.47) FFAR1LMNAGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0538955-B1 Anodes with extended service life and methods for their manufacturing MAGNETO CHEMIE BV (NL) 1998-02-04 EP disclosed
EP-0538955-A1 Anodes with extended service life and methods for their manufacturing MAGNETO-CHEMIE B.V. (NL) 1993-04-28 EP disclosed