Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.33 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3731633 | 0.93 | MAPT (0.45) | MAPTCKS1BSKP1SKP2ABL1 | |
| SCHEMBL7717128 | 0.88 | ABL1 (0.40) | MAPTCKS1BSKP1SKP2ABL1 | |
| SCHEMBL6046930 | 0.87 | MAPT (0.42) | MAPTCKS1BSKP1SKP2BRD4 | |
| SCHEMBL3670409 | 0.81 | RAB9A (0.47) | MAPTCKS1BSKP1SKP2ABL1 | |
| SCHEMBL8299962 | 0.79 | MEN1 (0.45) | MAPTABL1RIN1POLBP2RY6 | |
| SCHEMBL8646092 | 0.78 | FLT4 (0.40) | CKS1BSKP1SKP2ABL1HDAC1 | |
| SCHEMBL15234703 | 0.76 | CKS1B (0.42) | MAPTCKS1BSKP1SKP2BRD4 | |
| SCHEMBL14308496 | 0.76 | KMT2A (0.41) | MAPTCKS1BSKP1SKP2ABL1 | |
| SCHEMBL7867801 | 0.73 | MAPT (0.47) | MAPTABL1RIN1RAB9A | |
| SCHEMBL454099 | 0.72 | MAPT (0.50) | MAPTABL1RIN1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863150-A1 | A method for the preparation of nucleic acid binding compound | BOEHRINGER MANNHEIM GMBH (DE) | 1998-09-09 | — | — | EP | disclosed |