Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11196356 | 1.00 | NPSR1 (0.52) | NPSR1ALDH1A1HCAR2SOAT1SMN1; SMN2 | |
| SCHEMBL9427312 | 1.00 | NPSR1 (0.52) | NPSR1ALDH1A1HCAR2SOAT1SMN1; SMN2 | |
| SCHEMBL16068782 | 0.88 | HCAR2 (0.44) | NPSR1ALDH1A1HCAR2SOAT1SMN1; SMN2 | |
| SCHEMBL17469599 | 0.88 | NPSR1 (0.46) | NPSR1ALDH1A1HCAR2SOAT1SMN1; SMN2 | |
| SCHEMBL9718475 | 0.88 | ALDH1A1 (0.41) | NPSR1ALDH1A1HCAR2SOAT1SMN1; SMN2 | |
| SCHEMBL17469589 | 0.88 | NPSR1 (0.48) | NPSR1ALDH1A1HCAR2SOAT1SMN1; SMN2 | |
| SCHEMBL9718465 | 0.88 | ALDH1A1 (0.41) | NPSR1ALDH1A1HCAR2SOAT1SMN1; SMN2 | |
| SCHEMBL9718471 | 0.88 | ALDH1A1 (0.41) | NPSR1ALDH1A1HCAR2SOAT1SMN1; SMN2 | |
| SCHEMBL9777200 | 0.88 | NPSR1 (0.48) | NPSR1ALDH1A1HCAR2SOAT1SMN1; SMN2 | |
| SCHEMBL9777204 | 0.88 | NPSR1 (0.48) | NPSR1ALDH1A1HCAR2SOAT1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580444-B2 | Polycyclic pyrazolinone derivative and herbicide comprising same as effective component thereof | SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) | 2017-02-28 | — | — | US | disclosed |
| US-20160024110-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2016-01-28 | — | — | US | disclosed |
| EP-0573999-B1 | Process for preparation of alkyltetronates | LONZA AG (CH) | 1998-08-26 | — | — | EP | disclosed |
| US-5310947-A | Process for the production of tetronic acid alkyl esters | LONZA LTD. (CH) | 1994-05-10 | — | — | US | disclosed |
| EP-0346852-B1 | Process for producing 4-chloro-3-alkoxybut-2E-ene acid alkyl esters | LONZA AG (CH) | 1994-02-23 | — | — | EP | disclosed |
| EP-0573999-A1 | Process for preparation of alkyltetronates | LONZA AG (CH) | 1993-12-15 | — | — | EP | disclosed |
| US-4966989-A | KETALIZATION AND ESTERIFICATION OF 4-CHLOROACETOACETYL CHLORIDE WITH AN ALCOHOL AND A DIALKYL SULFITE | LONZA LTD. (CH) | 1990-10-30 | — | — | US | disclosed |
| EP-0346852-A2 | Process for producing 4-chloro-3-alkoxybut-2E-ene acid alkyl esters | LONZA AG (CH) | 1989-12-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024110-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | DDT, PDHX, CYP4X1 | NPSR1 2942/4885ALDH1A1 596/4885HCAR2 1561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.