Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718475 | 1.00 | ALDH1A1 (0.41) | ALDH1A1NPSR1MGAMGAASI | |
| SCHEMBL9718465 | 1.00 | ALDH1A1 (0.41) | ALDH1A1NPSR1MGAMGAASI | |
| SCHEMBL11196356 | 0.88 | NPSR1 (0.52) | ALDH1A1NPSR1MGAMGAASI | |
| SCHEMBL8646347 | 0.88 | NPSR1 (0.52) | ALDH1A1NPSR1MGAMGAASI | |
| SCHEMBL9427312 | 0.88 | NPSR1 (0.52) | ALDH1A1NPSR1MGAMGAASI | |
| SCHEMBL16068916 | 0.85 | HCAR2 (0.40) | ALDH1A1NPSR1HCAR2KEAP1NFE2L2 | |
| SCHEMBL17469589 | 0.84 | NPSR1 (0.48) | ALDH1A1NPSR1MGAMGAASI | |
| SCHEMBL9777204 | 0.84 | NPSR1 (0.48) | ALDH1A1NPSR1MGAMGAASI | |
| SCHEMBL9777200 | 0.84 | NPSR1 (0.48) | ALDH1A1NPSR1MGAMGAASI | |
| SCHEMBL19436648 | 0.83 | NPSR1 (0.42) | ALDH1A1NPSR1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5113012-A | PROCESS FOR THE PRODUCTION OF 1,3-CYCLOPENTANEDIONE | LONZA LTD. (CH) | 1992-05-12 | — | — | US | disclosed |
| US-5087760-A | PROCESS FOR THE PRODUCTION OF 1,3-CYCLOPENTANEDIONE | LONZA LTD. (CH) | 1992-02-11 | — | — | US | disclosed |