Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3633792 | 0.80 | USP2 (0.71) | USP2POLBALDH1A1GAAPKM | |
| SCHEMBL3373909 | 0.79 | USP2 (0.76) | USP2POLBALDH1A1GAAPKM | |
| SCHEMBL13271173 | 0.78 | USP2 (0.62) | USP2POLBALDH1A1GAAPKM | |
| SCHEMBL3843538 | 0.75 | CA12 (0.67) | ALDH1A1GAAPKMMEN1KMT2A | |
| SCHEMBL2706987 | 0.75 | USP2 (0.76) | USP2POLBALDH1A1GAAPKM | |
| SCHEMBL436674 | 0.75 | PKM (0.89) | USP2POLBALDH1A1GAAPKM | |
| SCHEMBL2705461 | 0.75 | L3MBTL1 (0.83) | USP2POLBALDH1A1GAAMEN1 | |
| SCHEMBL2112295 | 0.75 | USP2 (0.76) | USP2POLBALDH1A1GAAPKM | |
| SCHEMBL1046239 | 0.75 | USP2 (0.76) | USP2POLBALDH1A1GAAPKM | |
| SCHEMBL6748039 | 0.75 | USP2 (0.76) | USP2POLBALDH1A1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625516-B1 | Benzenesulphonamide derivatives for the treatment of bladder instability | ZENECA LTD (GB) | 1998-09-09 | — | — | EP | disclosed |
| US-5693639-A | TREATING URINARY INCONTINENCE | ZENECA LIMITED (GB) | 1997-12-02 | — | — | US | disclosed |
| US-5510386-A | ADMINISTERING TO RELAX SMOOTH MUSCLE OF THE BLADDER | ZENECA LIMITED (GB) | 1996-04-23 | — | — | US | disclosed |
| EP-0625516-A1 | Benzenesulphonamide derivatives for the treatment of bladder instability | ZENECA LIMITED (GB) | 1994-11-23 | — | — | EP | disclosed |