Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6262232 | 0.83 | ELANE (0.38) | ALOX15SMN1; SMN2RAB9AALDH1A1HSD17B10 | |
| SCHEMBL29044269 | 0.83 | ELANE (0.38) | ALOX15SMN1; SMN2RAB9AALDH1A1HSD17B10 | |
| SCHEMBL9028297 | 0.79 | ELANE (0.36) | ALOX15SMN1; SMN2KMT2ALMNAALDH1A1 | |
| SCHEMBL27848448 | 0.76 | ELANE (0.44) | ALOX15SMN1; SMN2KMT2AALDH1A1HSD17B10 | |
| SCHEMBL8646595 | 0.76 | AKR1B1 (0.49) | ALOX15KMT2AMEN1NPC1RAB9A | |
| SCHEMBL28935655 | 0.75 | ALDH1A1 (0.40) | ALOX15SMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL9380754 | 0.73 | ELANE (0.42) | ALOX15SMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL9028261 | 0.73 | ELANE (0.38) | ALOX15SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL4405818 | 0.73 | ELANE (0.45) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL1336622 | 0.73 | ELANE (0.45) | ALOX15SMN1; SMN2KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744635-A | REACTING THE CORRESPONDING HALOGEN SUBSTITUTED COMPOUND WITH AN ORGANOMETALLIC COMPOUND | Uclaf, Roussel (FR) | 1998-04-28 | — | — | US | disclosed |