Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | CPB1 | P15086 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8646125 | 0.99 | ITGB3 (0.36) | ITGB3ITGA2BITGAVTGM2CPB1 | |
| SCHEMBL8650056 | 0.90 | ITGB3 (0.35) | ITGB3ITGA2BITGAV | |
| SCHEMBL8650092 | 0.88 | ITGB3 (0.36) | ITGB3ITGA2BITGAVTGM2CPB1 | |
| SCHEMBL8642345 | 0.87 | ITGB3 (0.36) | ITGB3ITGA2BITGAVTGM2CPB1 | |
| SCHEMBL8645791 | 0.86 | — | — | |
| SCHEMBL8643523 | 0.84 | — | — | |
| SCHEMBL8647100 | 0.83 | ITGB3 (0.37) | ITGB3ITGA2BITGAVTGM2ALDH1A1 | |
| SCHEMBL8682769 | 0.80 | HTRA1 (0.36) | ITGB3ITGA2BTGM2 | |
| SCHEMBL8647489 | 0.79 | ITGB3 (0.43) | ITGB3ITGA2BITGAVTGM2 | |
| SCHEMBL8646093 | 0.78 | ITGB3 (0.40) | ITGB3ITGA2BITGAVTGM2CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710159-A | IMIDAZOLIN-2-YLAMINOPROPOXY)ISOXAZOL-5-CARBONYLAMINO-2 -BENZYLOXYCARBONYLAMINOPROPIONIC ACID AS ANTIINFLAMMATORY AGENTS, BONE DEGRADATION, TUMORS, METASTASES AND THROMBOSIS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-01-20 | — | — | US | claimed |
| US-5710159-A | IMIDAZOLIN-2-YLAMINOPROPOXY)ISOXAZOL-5-CARBONYLAMINO-2 -BENZYLOXYCARBONYLAMINOPROPIONIC ACID AS ANTIINFLAMMATORY AGENTS, BONE DEGRADATION, TUMORS, METASTASES AND THROMBOSIS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-01-20 | — | — | US | disclosed |