⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8150488 | 0.80 | — | — | |
| SCHEMBL6829993 | 0.80 | MGAM (0.48) | — | |
| SCHEMBL3503171 | 0.78 | — | — | |
| SCHEMBL1332051 | 0.78 | — | — | |
| SCHEMBL6638603 | 0.78 | — | — | |
| SCHEMBL4673728 | 0.78 | — | — | |
| SCHEMBL9199157 | 0.78 | — | — | |
| SCHEMBL11167447 | 0.76 | — | — | |
| SCHEMBL10390619 | 0.76 | — | — | |
| SCHEMBL17169822 | 0.76 | PAM (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180110862-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE | 2018-04-26 | — | — | US | disclosed |
| US-9867883-B2 | Isatoic anhydride derivatives and applications thereof | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2018-01-16 | — | — | US | disclosed |
| US-9867883-B2 | Isatoic anhydride derivatives and applications thereof | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2018-01-16 | — | — | US | disclosed |
| US-20170035893-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE | 2017-02-09 | — | — | US | disclosed |
| US-20170035893-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE | 2017-02-09 | — | — | US | disclosed |
| WO-2015163952-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2015-10-29 | — | — | WO | disclosed |
| EP-0679652-B1 | Process for preparing carbapenem compounds | SUMITOMO PHARMA (JP) | 1998-08-19 | — | — | EP | disclosed |
| US-5578722-A | Process for preparing carbapenem compounds | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0679652-A1 | Process for preparing carbapenem compounds | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1995-11-02 | — | — | EP | disclosed |
| EP-0419676-B1 | THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME | TEIJIN LTD (JP) | 1994-12-07 | — | — | EP | disclosed |
| EP-0419676-A1 | THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |
| US-3970678-A | Organotin mercaptide process | CINCINNATI MILACRON CHEMICALS, INC. (US) | 1976-07-20 | — | — | US | disclosed |