Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SI | P14410 | 2/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4848958 | 0.91 | GAA (0.65) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL9204032 | 0.90 | MGAM (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL6829994 | 0.88 | MGAM (0.37) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL11355140 | 0.84 | ALDH1A1 (0.34) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL16068775 | 0.83 | HSD17B10 (0.39) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL4673728 | 0.82 | — | — | |
| SCHEMBL9199157 | 0.82 | — | — | |
| SCHEMBL1332051 | 0.82 | — | — | |
| SCHEMBL6638603 | 0.82 | — | — | |
| SCHEMBL3503171 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230098847-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2023-03-30 | — | — | US | disclosed |
| US-11390585-B2 | Quaternary heteroatom containing compounds | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2022-07-19 | — | — | US | disclosed |
| WO-2004076425-A1 | IMPROVED SYNTHESIS OF MACROCYCLIC TETRAAMIDO COMPOUNDS AND NEW METAL INSERTION PROCESS | CARNEGIE MELLON UNIVERSITY (US) | 2004-09-10 | — | — | WO | disclosed |
| EP-0845466-B1 | Silicon containing filtering agents and cosmetic sunscreen compositions containing them | OREAL (FR) | 2000-01-19 | — | — | EP | disclosed |
| EP-0845466-A1 | Silicon containing filtering agents and cosmetic sunscreen compositions containing them | L'OREAL (FR) | 1998-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11390585-B2 | Quaternary heteroatom containing compounds | SDHA, NQO1, SDHB | MGAM 1904/4885GAA 1686/4885SI 3287/4885 |
| US-20230098847-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | SDHA, NQO1, SDHB | MGAM 1904/4885GAA 1686/4885SI 3287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.