SCHEMBL8648640

SCHEMBL8648640

CCCCC(CC)CNc1ccc2c(c1)C(=O)[N]C2=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.40
ALDH1A1 P00352 4/20 0.39
TSHR P16473 3/20 0.39
CYP3A4 P08684 1/20 0.39
PFKFB3 Q16875 1/20 0.37
CHEK1 O14757 1/20 0.37
KDM4E B2RXH2 3/20 0.36
HTT P42858 2/20 0.36
GLA P06280 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
NPY5R Q15761 1/20 0.36
P2RX7 Q99572 1/20 0.35
LMNA P02545 1/20 0.34
ATG4B Q9Y4P1 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
IGFBP3 P17936 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8648644 0.82 CHEK1 (0.56) GPR84ALDH1A1TSHRCYP3A4CHEK1
SCHEMBL1812493 0.78 ALDH1A1 (0.57) ALDH1A1TSHRCYP3A4PFKFB3KDM4E
SCHEMBL8749593 0.74 LMNA (0.60) ALDH1A1TSHRCYP3A4CHEK1KDM4E
SCHEMBL1170830 0.72 ALDH1A1 (0.49) ALDH1A1TSHRCYP3A4PFKFB3KDM4E
SCHEMBL24025159 0.72 ALDH1A1 (0.50) ALDH1A1TSHRCYP3A4PFKFB3KDM4E
SCHEMBL10583410 0.71 MAPT (0.43) ALDH1A1TSHRCYP3A4KDM4EHTT
SCHEMBL20353180 0.71 ALDH1A1 (0.48) ALDH1A1TSHRCYP3A4PFKFB3KDM4E
SCHEMBL11481208 0.71 ALDH1A1 (0.48) ALDH1A1TSHRCYP3A4PFKFB3KDM4E
SCHEMBL9114365 0.71 MAPT (0.50) ALDH1A1TSHRCYP3A4PFKFB3KDM4E
SCHEMBL18424569 0.71 ALDH1A1 (0.44) ALDH1A1TSHRCYP3A4KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0487081-B1 Silver halide color photographic materials FUJI PHOTO FILM CO LTD (JP) 1998-09-09 EP disclosed
US-5342749-A Silver halide color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1994-08-30 US disclosed
EP-0487081-A1 Silver halide color photographic materials FUJI PHOTO FILM CO., LTD (JP) 1992-05-27 EP disclosed