Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | CDK4 | P11802 | 3/20 | 0.41 |
| ▸ | CCND1 | P24385 | 3/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27812843 | 0.90 | CDK4 (0.44) | EGFRPRKCIHTR2CHTR2ACDK4 | |
| SCHEMBL3650822 | 0.86 | PRKCI (0.59) | EGFRPRKCIHTR2CHTR2ACDK4 | |
| SCHEMBL3345985 | 0.85 | PRKCI (0.44) | PRKCIHTR2CHTR2AMTNR1AMTNR1B | |
| SCHEMBL23413236 | 0.84 | KMO (0.44) | PRKCIHTR2CHTR2ACDK4CCND1 | |
| SCHEMBL29780573 | 0.84 | KMO (0.44) | PRKCIHTR2CHTR2ACDK4CCND1 | |
| SCHEMBL1122347 | 0.81 | HTR2C (0.64) | HTR2CHTR2AHTR1DHTR6 | |
| SCHEMBL19173629 | 0.80 | HTR2A (0.58) | HTR2CHTR2ACDK4CCND1MTNR1A | |
| SCHEMBL12857017 | 0.79 | CDK4 (0.44) | PRKCICDK4CCND1HTR6KMO | |
| SCHEMBL8265371 | 0.79 | MCL1 (0.46) | PRKCIHTR2CHTR2ACDK4CCND1 | |
| SCHEMBL31444642 | 0.79 | PRKCI (0.40) | PRKCIHTR2CHTR2ACDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578735-B1 | NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS | OREAL (FR) | 1996-01-03 | — | — | EP | claimed |
| EP-0580713-B1 | METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR | OREAL (FR) | 1995-03-01 | — | — | EP | claimed |
| EP-0580713-A1 | METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR. | OREAL (FR) | 1994-02-02 | — | — | EP | claimed |
| EP-0578735-A1 | NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS. | OREAL (FR) | 1994-01-19 | — | — | EP | claimed |
| WO-1992018093-A1 | METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR | L'OREAL (FR) | 1992-10-29 | — | — | WO | claimed |
| WO-1992017157-A1 | NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS | L'OREAL (FR) | 1992-10-15 | — | — | WO | claimed |
| EP-2915804-B1 | NOVEL AMINE DERIVATIVE OR SALT THEREOF AS TNF ALPHA INHIBITORS | FUJIFILM TOYAMA CHEMICAL CO LTD (JP) | 2019-03-27 | — | — | EP | disclosed |
| EP-2915804-B1 | NOVEL AMINE DERIVATIVE OR SALT THEREOF AS TNF ALPHA INHIBITORS | FUJIFILM TOYAMA CHEMICAL CO LTD (JP) | 2019-03-27 | — | — | EP | disclosed |
| US-9624215-B2 | Amine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2017-04-18 | — | — | US | disclosed |
| US-9624215-B2 | Amine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2017-04-18 | — | — | US | disclosed |
| US-9624215-B2 | Amine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2017-04-18 | — | — | US | disclosed |
| US-20150299189-A1 | NOVEL AMINE DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2015-10-22 | — | — | US | disclosed |
| US-20150299189-A1 | NOVEL AMINE DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2015-10-22 | — | — | US | disclosed |
| US-5752982-A | DYEING HAIR IN LIGHTFAST, WASHFAST COLORS | L'OREAL (FR) | 1998-05-19 | — | — | US | disclosed |
| EP-0578735-B1 | NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS | OREAL (FR) | 1996-01-03 | — | — | EP | disclosed |
| EP-0580713-B1 | METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR | OREAL (FR) | 1995-03-01 | — | — | EP | disclosed |
| EP-0580713-A1 | METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR. | OREAL (FR) | 1994-02-02 | — | — | EP | disclosed |
| EP-0578735-A1 | NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS. | OREAL (FR) | 1994-01-19 | — | — | EP | disclosed |
| WO-1992018093-A1 | METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR | L'OREAL (FR) | 1992-10-29 | — | — | WO | disclosed |
| WO-1992017157-A1 | NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS | L'OREAL (FR) | 1992-10-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150299189-A1 | NOVEL AMINE DERIVATIVE OR SALT THEREOF | HRH4, CLIC4, KRT18 | EGFR 537/4885PRKCI 1739/4885HTR2C 3391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.