Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18749637 | 0.86 | MRGPRX4 (0.49) | TDP1MAPTPOLBTSHRL3MBTL1 | |
| SCHEMBL28334171 | 0.86 | SMN1; SMN2 (0.52) | TDP1MAPTPOLBTSHRALDH1A1 | |
| SCHEMBL18749771 | 0.85 | MAPT (0.44) | MAPTNPSR1RECQLALDH1A1PTGDR2 | |
| SCHEMBL4114001 | 0.84 | RXRA (0.55) | RXRARXRBRXRGNPSR1RECQL | |
| SCHEMBL8467383 | 0.84 | TDP1 (0.43) | RXRARXRBRXRGTDP1MAPT | |
| SCHEMBL7174468 | 0.84 | TP53 (0.58) | RXRARXRBMAPTNPSR1TSHR | |
| SCHEMBL18515095 | 0.83 | FFAR4 (0.50) | MAPTALDH1A1 | |
| SCHEMBL18749543 | 0.82 | LMNA (0.44) | MAPTPTGDR2LMNA | |
| SCHEMBL18749540 | 0.82 | PARP10 (0.39) | TDP1MAPTL3MBTL1ALDH1A1PTGDR2 | |
| SCHEMBL18514413 | 0.82 | PTGDR2 (0.40) | MAPTNPSR1ALDH1A1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710314-A | FUNGICIDES OR INSECTICIDES OF AROMATIC ETHERS WITH ESTER GROUPS OR AMIDES | NOVARTIS CORPORATION (US) | 1998-01-20 | — | — | US | disclosed |
| EP-0784606-A1 | MICROBICIDES | Novartis AG (CH) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010556-A1 | MICROBICIDES | NOVARTIS AG (CH) | 1996-04-11 | — | — | WO | disclosed |