Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8645371 | 0.99 | KMT2A (0.73) | KMT2AALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL8646474 | 0.86 | ALDH1A1 (0.63) | KMT2AALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL8644045 | 0.86 | ALDH1A1 (0.81) | KMT2AALDH1A1MEN1CYP3A4CYP2C9 | |
| SCHEMBL31195227 | 0.86 | ALDH1A1 (0.72) | KMT2AALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL10282744 | 0.84 | KMT2A (0.61) | KMT2AALDH1A1TSHRLMNATDP1 | |
| SCHEMBL4070839 | 0.84 | ALDH1A1 (0.84) | KMT2AALDH1A1TSHRLMNATDP1 | |
| SCHEMBL3300404 | 0.82 | ALDH1A1 (0.84) | KMT2AALDH1A1TSHRLMNATDP1 | |
| SCHEMBL17131816 | 0.81 | TSHR (0.77) | KMT2AALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL31195221 | 0.81 | ALDH1A1 (0.66) | KMT2AALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL165282 | 0.81 | KMT2A (0.69) | KMT2AALDH1A1HSD17B10LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625516-B1 | Benzenesulphonamide derivatives for the treatment of bladder instability | ZENECA LTD (GB) | 1998-09-09 | — | — | EP | claimed |
| EP-0625516-A1 | Benzenesulphonamide derivatives for the treatment of bladder instability | ZENECA LIMITED (GB) | 1994-11-23 | — | — | EP | claimed |
| EP-2258356-B1 | CHEMICAL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST DENGUE VIRUS AND OTHER FLAVIVIRUSES | CT INGENIERIA GENETICA BIOTECNOLOGIA (CU) | 2017-09-27 | — | — | EP | disclosed |
| EP-0625516-B1 | Benzenesulphonamide derivatives for the treatment of bladder instability | ZENECA LTD (GB) | 1998-09-09 | — | — | EP | disclosed |
| EP-0625516-A1 | Benzenesulphonamide derivatives for the treatment of bladder instability | ZENECA LIMITED (GB) | 1994-11-23 | — | — | EP | disclosed |