SCHEMBL8649263

SCHEMBL8649263

C=CC(=C)[Si](C)(C)O[Si](C)(C)C(=C)C=C

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TP53 P04637 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10348359 0.80
SCHEMBL10348462 0.74 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL8651889 0.72 ALDH1A1 (0.32) ALDH1A1TP53TSHR
SCHEMBL3056449 0.71
SCHEMBL31707460 0.71 ALDH1A1 (0.41) ALDH1A1TP53TSHR
SCHEMBL9492037 0.69 ALDH1A1 (0.33) ALDH1A1TP53TSHR
SCHEMBL7913331 0.67
SCHEMBL8650665 0.65 ALDH1A1 (0.30) ALDH1A1TP53TSHR
SCHEMBL8650402 0.65
SCHEMBL2496519 0.65 ALDH1A1 (0.35) ALDH1A1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5059705-A Intermediate or modifying agent in synthesis of silicone resins or other resins SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-10-22 US claimed
EP-0444920-A2 Butadienyl groupcontaining siloxane compounds and method of producing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-09-04 EP claimed
JP-4211426-A None JP disclosed
JP-4211091-A None JP disclosed
US-20250326871-A1 POLYDIENES WITH REDUCED SOLUTION VISCOSITY GOODYEAR TIRE & RUBBER (US) 2025-10-23 US disclosed
EP-4635996-A1 POLYDIENES WITH REDUCED SOLUTION VISCOSITY The Goodyear Tire & Rubber Company (US) 2025-10-22 EP disclosed
EP-0444920-B1 Butadienyl groupcontaining siloxane compounds and method of producing the same SHINETSU CHEMICAL CO (JP) 1998-09-16 EP disclosed
EP-0444921-B1 Siloxane compound containing tetrahydrophthalic anhydride group and method of producing the same SHINETSU CHEMICAL CO (JP) 1997-05-07 EP disclosed
JP-H04211426-A BUTADIENYL GROUP-CONTAINING SILOXANE COMPOUND AND PRODUCTION THEREOF SHIN ETSU CHEM CO LTD 1992-08-03 JP disclosed
JP-H04211091-A CYCLOHEXANE COMPOUND HAVING TETRAHYDROPHTHALIC ANHYDRIDE GROUP AND PRODUCTION THEREOF SHIN ETSU CHEM CO LTD 1992-08-03 JP disclosed
US-5117001-A SILOXANE COMPOUND CONTAINING TETRAHYDROPHTHALIC ANHYDRIDE GROUP AND METHOD OF PRODUCING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-05-26 US disclosed
US-5059705-A Intermediate or modifying agent in synthesis of silicone resins or other resins SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-10-22 US disclosed
EP-0444920-A2 Butadienyl groupcontaining siloxane compounds and method of producing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-09-04 EP disclosed
EP-0444921-A2 Siloxane compound containing tetrahydrophthalic anhydride group and method of producing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-09-04 EP disclosed