Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8608518 | 0.83 | TSHR (0.41) | TDP1TSHR | |
| SCHEMBL10835235 | 0.77 | LMNA (0.39) | LMNATSHR | |
| SCHEMBL2908111 | 0.75 | LMNA (0.43) | LMNATSHR | |
| SCHEMBL6847774 | 0.75 | LMNA (0.42) | LMNAL3MBTL1TDP1TSHRKDM4E | |
| SCHEMBL19419877 | 0.75 | LMNA (0.42) | LMNAL3MBTL1TDP1TSHRKDM4E | |
| SCHEMBL3403121 | 0.75 | LMNA (0.42) | LMNAL3MBTL1TDP1TSHRKDM4E | |
| SCHEMBL1104153 | 0.74 | — | — | |
| SCHEMBL10767247 | 0.73 | LMNA (0.41) | LMNATSHRKDM4E | |
| SCHEMBL10773007 | 0.72 | TRPA1 (0.45) | TDP1TSHR | |
| SCHEMBL8431961 | 0.72 | LMNA (0.40) | LMNAL3MBTL1TDP1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731476-A | Poly ether preparation | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1998-03-24 | — | — | US | disclosed |