Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | IDH2 | P48735 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8649667 | 0.97 | DHFR (0.35) | GAAGRM2TSHRALDH1A1POLB | |
| SCHEMBL8649996 | 0.91 | GAA (0.35) | GAAALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL8649686 | 0.91 | TSHR (0.38) | GAAGRM2TSHRALDH1A1POLB | |
| SCHEMBL8321358 | 0.90 | GAA (0.35) | GAATSHRALDH1A1POLBHTT | |
| SCHEMBL8648970 | 0.90 | TSHR (0.36) | GRM2TSHRALDH1A1HTTDHFR | |
| SCHEMBL8651820 | 0.88 | GAA (0.32) | GAAKMT2AMEN1SMN1; SMN2TP53 | |
| SCHEMBL8645101 | 0.88 | DHFR (0.40) | GRM2TSHRDHFRKMT2AMEN1 | |
| SCHEMBL8322230 | 0.87 | DHFR (0.36) | GAAALDH1A1POLBDHFR | |
| SCHEMBL8648781 | 0.87 | DHFR (0.38) | GRM2TSHRHTTDHFRKMT2A | |
| SCHEMBL8322550 | 0.87 | GAA (0.37) | GAATSHRALDH1A1POLBDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824824-A | AROMATIC SULFONATE ANIONS AND DISSOLUTION CONTRAST IN EXPOSED AND NONEXPOSED AREAS, POSITIVE RESISTS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |