Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | IDH2 | P48735 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648970 | 0.97 | TSHR (0.36) | TSHRDHFRIDH2TP53GRM2 | |
| SCHEMBL8645101 | 0.97 | DHFR (0.40) | TSHRDHFRIDH2TP53GRM2 | |
| SCHEMBL8648781 | 0.94 | DHFR (0.38) | TSHRDHFRIDH2TP53GRM2 | |
| SCHEMBL8649673 | 0.91 | GAA (0.34) | TSHRDHFRIDH2TP53GRM2 | |
| SCHEMBL8649667 | 0.88 | DHFR (0.35) | TSHRDHFRIDH2GRM2MEN1 | |
| SCHEMBL8649071 | 0.87 | LMNA (0.36) | TSHRIDH2MEN1KMT2ALMNA | |
| SCHEMBL8645300 | 0.86 | CXCR4 (0.34) | TSHRIDH2MEN1KMT2ALMNA | |
| SCHEMBL8646299 | 0.84 | MEN1 (0.34) | TSHRDHFRIDH2MEN1KMT2A | |
| SCHEMBL8649231 | 0.83 | TP53 (0.41) | TSHRDHFRTP53MEN1KMT2A | |
| SCHEMBL8324624 | 0.83 | DHFR (0.43) | TSHRDHFRTP53HSD11B1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824824-A | AROMATIC SULFONATE ANIONS AND DISSOLUTION CONTRAST IN EXPOSED AND NONEXPOSED AREAS, POSITIVE RESISTS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |