Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 8/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.52 |
| ▸ | PGR | P06401 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | RORA | P35398 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | RORB | Q92753 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10994498 | 0.85 | PLK1 (0.47) | PLK1APOBEC3GPGRCNR2RORA | |
| SCHEMBL10991227 | 0.73 | PGR (0.49) | PLK1APOBEC3GPGRCNR2RORA | |
| SCHEMBL12963428 | 0.72 | PGR (0.61) | PLK1APOBEC3GPGRCNR2RORA | |
| SCHEMBL11462755 | 0.69 | APEX1 (0.55) | PLK1APOBEC3GPGRGAAKDM4E | |
| SCHEMBL24324198 | 0.69 | PLK1 (1.00) | PLK1APOBEC3GGAANPC1 | |
| SCHEMBL13386557 | 0.69 | ALDH1A1 (0.71) | PGRRORARORCRORBGAA | |
| SCHEMBL6400912 | 0.68 | PGR (0.64) | PLK1APOBEC3GPGRCNR2RORA | |
| SCHEMBL12963546 | 0.68 | PGR (0.59) | PLK1PGRCNR2RORARORC | |
| SCHEMBL24324227 | 0.68 | PLK1 (1.00) | PLK1APOBEC3GGAANPC1SMN1; SMN2 | |
| SCHEMBL153959 | 0.67 | ALDH1A1 (0.62) | PGRCNR2RORARORCRORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946095-A1 | FUNGICIDAL QUINAZOLINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998026664-A1 | FUNGICIDAL QUINAZOLINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |