Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.32 |
| ▸ | TUBB | P07437 | 3/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.32 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.32 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642034 | 0.88 | KRAS (0.32) | KRASTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8646870 | 0.88 | HSP90AA1 (0.34) | KRASTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8645276 | 0.88 | HSP90AA1 (0.33) | KRASTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8661489 | 0.88 | KRAS (0.31) | KRASTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8643266 | 0.87 | KRAS (0.32) | KRASTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8649362 | 0.86 | ALDH1A1 (0.32) | KRASTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8645256 | 0.85 | ALDH1A1 (0.31) | KRASTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8645270 | 0.84 | KRAS (0.30) | KRASTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8646579 | 0.82 | TUBB4A (0.31) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8642654 | 0.80 | KRAS (0.31) | KRASTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997041100-A1 | IMINOXY DERIVATIVES OF INDOLE AND INDENE COMPOUNDS AS INHIBITORS OF PROSTAGLANDIN BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1997-11-06 | — | — | WO | claimed |
| US-5756531-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1998-05-26 | — | — | US | disclosed |
| WO-1997041100-A1 | IMINOXY DERIVATIVES OF INDOLE AND INDENE COMPOUNDS AS INHIBITORS OF PROSTAGLANDIN BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1997-11-06 | — | — | WO | disclosed |