Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 2/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2096002 | 0.81 | NOS3 (0.46) | GBA1CCR3CARM1PRMT6NOS1 | |
| SCHEMBL8644802 | 0.78 | GBA1 (0.43) | GBA1CCR3CARM1PRMT6NOS1 | |
| SCHEMBL4609517 | 0.74 | GBA1 (0.50) | GBA1CCR3 | |
| SCHEMBL42600 | 0.74 | GBA1 (0.59) | GBA1CCR3CARM1PRMT6PRMT3 | |
| SCHEMBL16191140 | 0.73 | GBA1 (0.48) | GBA1CCR3CARM1PRMT6NOS1 | |
| SCHEMBL27439538 | 0.73 | GBA1 (0.48) | GBA1CCR3 | |
| SCHEMBL21494673 | 0.71 | GBA1 (0.47) | GBA1CCR3CARM1PRMT6 | |
| SCHEMBL1830037 | 0.71 | NOS3 (0.50) | GBA1CCR3NOS1NOS2NOS3 | |
| SCHEMBL1366152 | 0.71 | GBA1 (0.50) | GBA1CCR3CARM1PRMT6NOS1 | |
| SCHEMBL6051971 | 0.70 | GRIN2B (0.49) | CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773437-A | UROGENITAL DISORDERS SUCH AS DYSURIA | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |