Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.59 |
| ▸ | CCR3 | P51677 | 3/20 | 0.53 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1366152 | 0.88 | GBA1 (0.50) | GBA1CCR3PRMT3CARM1PRMT6 | |
| SCHEMBL2027845 | 0.84 | GBA1 (0.71) | GBA1CCR3PRMT3CARM1PRMT6 | |
| SCHEMBL674276 | 0.84 | GBA1 (0.71) | GBA1CCR3PRMT3CARM1PRMT6 | |
| Ammonia Solution, Strong SCHEMBL1432566 | 0.81 | GBA1 (0.68) | GBA1CCR3PRMT3CARM1PRMT6 | |
| SCHEMBL8776715 | 0.81 | CCR3 (0.57) | CCR3PRMT3CARM1PRMT6PRMT1 | |
| Hydrochloric Acid SCHEMBL4797146 | 0.79 | GBA1 (0.65) | GBA1CCR3PRMT3CARM1PRMT6 | |
| SCHEMBL8701 | 0.79 | GBA1 (0.65) | GBA1CCR3PRMT3CARM1PRMT6 | |
| SCHEMBL316482 | 0.79 | GBA1 (0.65) | GBA1CCR3PRMT3CARM1PRMT6 | |
| SCHEMBL240002 | 0.79 | MAOA (0.50) | CARM1PRMT6 | |
| SCHEMBL3130172 | 0.79 | ALDH1A1 (0.51) | CCR3GRIN2BTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118047726-A | Ferulic acid ester analogues, preparation method and application thereof | 西北大学 | 2024-05-17 | — | — | CN | claimed |
| CN-117946031-A | Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors | 北京大学 | 2024-04-30 | — | — | CN | claimed |
| US-20240018119-A1 | CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS | TRINEURO (KR) | 2024-01-18 | — | — | US | claimed |
| US-20230212144-A1 | 5-MEMBERED HETEROARYL DERIVATIVE CONTAINING AT LEAST ONE N, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MENTAL DISORDERS, CONTAINING SAME AS ACTIVE INGREDIENT | TRINEURO (KR) | 2023-07-06 | — | — | US | claimed |
| CN-113773289-B | Naphthalene [1,2-b ] heterocycle-4, 5-diketone compound and preparation method and application thereof | 沈阳药科大学 | 2023-05-12 | — | — | CN | claimed |
| CN-116057049-A | Carboxamide derivatives and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient | 大邱庆北尖端医疗产业振兴财团 | 2023-05-02 | — | — | CN | claimed |
| CN-116057053-A | 5-membered heteroaryl derivatives containing at least one N and pharmaceutical compositions containing the same as active ingredient for preventing or treating mental disorders | 大邱庆北尖端医疗产业振兴财团 | 2023-05-02 | — | — | CN | claimed |
| CN-114315689-B | Disulfanylphthalimide compound, preparation method and application thereof | 四川大学 | 2023-04-07 | — | — | CN | claimed |
| CN-114805367-B | Triazole pyrimidine derivative and preparation method and application thereof | 郑州大学 | 2023-04-07 | — | — | CN | claimed |
| WO-2023001268-A1 | CHRYSIN DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 深圳枫语生物医药科技有限公司 | 2023-01-26 | — | — | WO | claimed |
| US-4576943-A | NERVOUS SYSTEM DISORDERS, SEDATIVES, HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1986-03-18 | — | — | US | claimed |
| US-4569994-A | Dibenzo[b,d]pyranyloxyaminopropanols | PENNWALT CORPORATION | 1986-02-11 | — | — | US | claimed |
| EP-0155809-A2 | Renin inhibitors containing statine or derivatives thereof | PFIZER INC. (US) | 1985-09-25 | — | — | EP | claimed |
| EP-0039051-B1 | MANNICH-BASE HYDROXAMIC ACID PRODRUGS FOR THE IMPROVED BIOAVAILABILITY OF NON-STEROIDAL ANTI-INFLAMMATORY AGENTS, A PROCESS FOR PREPARING AND A PHARMACEUTICAL COMPOSITION CONTAINING THEM | MERCK & CO. INC. (US) | 1985-07-24 | — | — | EP | claimed |
| US-4412994-A | AMINE COMPOUNDS CONTAINING THE ACYL RESIDUE OF INDOMETHACIN AS A SUBSTITUENT | INTERX RESEARCH CORPORATION (US) | 1983-11-01 | — | — | US | claimed |
| EP-0051278-A1 | Soft tertiary amine esters of bio-affecting carboxylic acids, processes for preparing and a pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1982-05-12 | — | — | EP | claimed |
| WO-1982001186-A1 | NOVEL BENZOXAZOLINONES,SUBSTITUTED IN THE 6-POSITION BY AN AMINOALCOHOL CHAIN OR AMINO-KETONE CHAIN,THEIR PREPARATION AND THEIR USE IN PHARMACEUTICAL PREPARATIONS | BUSCH N | 1982-04-15 | — | — | WO | claimed |
| EP-0039051-A2 | Mannich-base hydroxamic acid prodrugs for the improved bioavailability of non-steroidal anti-inflammatory agents, a process for preparing and a pharmaceutical composition containing them | MERCK & CO. INC. (US) | 1981-11-04 | — | — | EP | claimed |
| EP-0007067-A1 | Phenylpiperidine derivatives, processes for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1980-01-23 | — | — | EP | claimed |
| US-4139626-A | FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1979-02-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018119-A1 | CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS | MAOA, DRD2, MAOB | GBA1 1662/4885CCR3 4856/4885PRMT3 1595/4885 |
| US-20230212144-A1 | 5-MEMBERED HETEROARYL DERIVATIVE CONTAINING AT LEAST ONE N, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MENTAL DISORDERS, CONTAINING SAME AS ACTIVE INGREDIENT | HTR5A, HTR2C, TPH1 | GBA1 2395/4885CCR3 4875/4885PRMT3 2338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.