Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 9/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 8/20 | 0.33 |
| ▸ | CA12 | O43570 | 7/20 | 0.33 |
| ▸ | CA9 | Q16790 | 7/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8647646 | 0.95 | ELANE (0.44) | ELANEKDM1ACA2MAPTPOLB | |
| SCHEMBL8648957 | 0.85 | ELANE (0.38) | ELANEKDM1ACA2PKMSTS | |
| SCHEMBL8643879 | 0.85 | ELANE (0.36) | ELANECA2KMT2AALDH1A1HSD11B1 | |
| SCHEMBL5406984 | 0.81 | CA1 (0.36) | ELANECA2PKMCA1CA12 | |
| SCHEMBL8319678 | 0.81 | ELANE (0.55) | ELANEKDM1ACA2MAPTPOLB | |
| SCHEMBL8969045 | 0.80 | ELANE (0.51) | ELANEKDM1ACA2MAPTPOLB | |
| SCHEMBL8645077 | 0.78 | PSEN1 (0.44) | CA2MAPTPOLBPKMCA1 | |
| SCHEMBL8649803 | 0.77 | ELANE (0.48) | ELANEKDM1ACA2MAPTPOLB | |
| SCHEMBL8643779 | 0.77 | ELANE (0.48) | ELANEKDM1ACA2MAPTPOLB | |
| SCHEMBL2903713 | 0.76 | CA1 (0.35) | CA2CA1CA12KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824824-A | AROMATIC SULFONATE ANIONS AND DISSOLUTION CONTRAST IN EXPOSED AND NONEXPOSED AREAS, POSITIVE RESISTS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |