SCHEMBL8969045

SCHEMBL8969045

CC(C)(C)OC(=O)Oc1ccc(S(OS(=O)(=O)C(F)(F)F)(c2ccc(OC(=O)OC(C)(C)C)cc2)c2ccc(OC(=O)OC(C)(C)C)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.51
KDM1A O60341 1/20 0.40
CA2 P00918 6/20 0.39
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
PKM P14618 1/20 0.37
HSD11B1 P28845 1/20 0.36
CA12 O43570 5/20 0.35
CA1 P00915 5/20 0.35
CA9 Q16790 5/20 0.35
MMP13 P45452 2/20 0.34
CA14 Q9ULX7 1/20 0.34
KMT2A Q03164 1/20 0.34
STS P08842 1/20 0.33
CXCR2 P25025 1/20 0.33
PRTN3 P24158 1/20 0.33
PSEN1 P49768 1/20 0.33
PSEN2 P49810 1/20 0.33
APH1B Q8WW43 1/20 0.33
NCSTN Q92542 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8319678 0.84 ELANE (0.55) ELANEKDM1ACA2POLBMAPT
SCHEMBL3694543 0.84 ELANE (0.41) ELANEKDM1ACA2HSD11B1CA1
SCHEMBL8643779 0.83 ELANE (0.48) ELANEKDM1ACA2POLBMAPT
SCHEMBL8323469 0.82 ELANE (0.50) ELANEKDM1ACA2POLBMAPT
SCHEMBL8643863 0.81 ELANE (0.44) ELANEKDM1ACA2HSD11B1MMP13
SCHEMBL8649154 0.81 ELANE (0.44) ELANEKDM1ACA2HSD11B1MMP13
SCHEMBL8081860 0.80 PSEN1 (0.53) CA2POLBCA12CA1CA9
SCHEMBL8649808 0.80 ELANE (0.48) ELANEKDM1ACA2POLBMAPT
SCHEMBL66113 0.79 HSD11B1 (0.38) ELANECA2PKMHSD11B1CA1
SCHEMBL3421884 0.79 MAPT (0.53) ELANEPOLBMAPTPKMHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5563022-A MIXTURE OF WATER INSOLUBLE ORGANIC BINDER HAVING ACID-LABILE ETHER, ESTER OR CARBONATE GROUPS OR BEING SOLUBLE IN ALKALINE SOLUTIONS, ORGANIC COMPOUND WHOSE SOLUBILITY IS INCREASED BY ACID, ARYLSULFONIC ESTER BASF AKTIENGESELLSCHAFT (DE) 1996-10-08 US disclosed
US-5318876-A Solutions of water insoluble, base soluble polymeric binder, substituted sulfonium salts, substituted benzenesulfonates, having tolerance for delay between exposure and heating to develop BASF AKTIENGESELLSCHAFT (DE) 1994-06-07 US disclosed
US-5300400-A Process for the production of relief patterns and images utilizing an organic compound having at least one acid-cleavable group and a storage stability improving amount of a second organic compound BASF AKTIENGESELLSCHAFT (DE) 1994-04-05 US disclosed