SCHEMBL8650267

SCHEMBL8650267

CCCON(C(=O)OC(C)(C)C)C(Cc1ccccc1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.42
HDAC3 O15379 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
NCOR2 Q9Y618 1/20 0.40
ATM Q13315 1/20 0.39
ITGA4 P13612 1/20 0.39
ITGB7 P26010 1/20 0.39
ACE P12821 1/20 0.39
AKT1 P31749 1/20 0.38
CTSS P25774 2/20 0.38
MAPT P10636 1/20 0.38
CTSL P07711 1/20 0.38
CTSB P07858 1/20 0.38
CTSK P43235 1/20 0.38
SLC7A5 Q01650 1/20 0.38
PPARG P37231 2/20 0.37
PPARA Q07869 2/20 0.37
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11888719 0.84 ITGA4 (0.44) L3MBTL1ATMITGA4ITGB7ACE
SCHEMBL1310667 0.84 ITGA4 (0.44) L3MBTL1ATMITGA4ITGB7ACE
SCHEMBL8392929 0.80 ATM (0.45) L3MBTL1ATMITGA4ITGB7ACE
SCHEMBL9321962 0.80 ATM (0.45) L3MBTL1ATMITGA4ITGB7ACE
SCHEMBL11651226 0.80 ATM (0.45) L3MBTL1ATMITGA4ITGB7ACE
SCHEMBL11566665 0.80 HDAC3 (0.41) L3MBTL1HDAC3HDAC1HDAC2NCOR2
SCHEMBL31387574 0.80 L3MBTL1 (0.41) L3MBTL1HDAC3HDAC1HDAC2NCOR2
SCHEMBL23099848 0.79 ATM (0.42) L3MBTL1HDAC3HDAC1HDAC2NCOR2
SCHEMBL10957821 0.79 ATM (0.42) L3MBTL1HDAC3HDAC1HDAC2NCOR2
SCHEMBL10957808 0.79 ATM (0.42) L3MBTL1HDAC3HDAC1HDAC2NCOR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5714497-A EXHIBIT AFFINITY FOR BIOLOGICAL RECEPTORS OF NEUROPEPTIDE Y SANOFI (FR) 1998-02-03 US disclosed