Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.45 |
| ▸ | CTSG | P08311 | 4/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.45 |
| ▸ | CMA1 | P23946 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642814 | 0.83 | GAA (0.39) | RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL8642824 | 0.83 | GAA (0.39) | RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL8645969 | 0.82 | F10 (0.40) | PRSS1 | |
| SCHEMBL8650390 | 0.82 | HDAC3 (0.41) | PPARARAB9AMEN1KMT2ANPC1 | |
| SCHEMBL8644172 | 0.82 | SCN5A (0.37) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8644799 | 0.81 | F10 (0.40) | PRSS1 | |
| SCHEMBL8647713 | 0.81 | POLB (0.35) | PPARARAB9AMEN1KMT2ANPC1 | |
| Iodide SCHEMBL8645881 | 0.81 | POLB (0.34) | PPARARAB9AMEN1KMT2ANPC1 | |
| SCHEMBL8642834 | 0.80 | RAB9A (0.40) | PPARARAB9AKMT2ANPC1MAPT | |
| SCHEMBL8644180 | 0.79 | POLB (0.39) | PPARARAB9AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726185-A | BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELET AGGREGATION AND CELL TO CELL ADHESION | HOFFMANN-LA ROCHE INC. (US) | 1998-03-10 | — | — | US | disclosed |