Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 19/20 | 0.62 |
| ▸ | ATP4B | P51164 | 19/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8649873 | 0.84 | ATP4A (0.60) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL9569756 | 0.81 | ATP4A (0.50) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL8993822 | 0.79 | ATP4A (0.48) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL8993812 | 0.79 | ATP4A (0.48) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL3602906 | 0.77 | MEN1 (0.58) | NPC1MAPTRAB9A | |
| SCHEMBL4109611 | 0.77 | ATP4A (1.00) | ATP4AATP4BNPC1MAPTRAB9A | |
| Bromide SCHEMBL826017 | 0.76 | ATP4A (1.00) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL9298559 | 0.74 | ATP4A (0.59) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL2395283 | 0.74 | ATP4A (0.73) | ATP4AATP4BNPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL8648866 | 0.73 | ATP4A (0.74) | ATP4AATP4BNPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545376-B1 | Guanidino thiazoles and their use as H2-receptor antagonist | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-09-09 | — | — | EP | disclosed |
| US-5532258-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| CN-1089259-A | New compound | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-07-13 | — | — | CN | disclosed |
| CN-1079469-A | Preparation method with thiazole derivative of antiulcer activity and Histamine Receptors antagonistic action | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-12-15 | — | — | CN | disclosed |
| EP-0545376-A1 | Guanidino thiazoles and their use as H2-receptor antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |