Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 18/20 | 0.48 |
| ▸ | ATP4B | P51164 | 18/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993822 | 1.00 | ATP4A (0.48) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL8649873 | 0.83 | ATP4A (0.60) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL9569756 | 0.81 | ATP4A (0.50) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL8650286 | 0.79 | ATP4A (0.62) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL9297884 | 0.78 | NPC1 (0.43) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL9297599 | 0.78 | NPC1 (0.43) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL9298140 | 0.77 | ATP4A (0.45) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL9298148 | 0.77 | ATP4A (0.45) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL9292417 | 0.76 | NPC1 (0.42) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL9292416 | 0.76 | NPC1 (0.42) | ATP4AATP4BNPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532258-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0545376-A1 | Guanidino thiazoles and their use as H2-receptor antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |