Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525076 | 0.89 | MEN1 (0.40) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL8525079 | 0.89 | MEN1 (0.40) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL8525431 | 0.87 | EGFR (0.37) | JAK2JAK3 | |
| SCHEMBL8490387 | 0.84 | — | — | |
| SCHEMBL8490025 | 0.71 | IRAK4 (0.45) | — | |
| SCHEMBL8524823 | 0.70 | — | — | |
| SCHEMBL8120079 | 0.69 | TP53 (0.33) | JAK2JAK1JAK3 | |
| SCHEMBL8493726 | 0.69 | IRAK4 (0.44) | — | |
| SCHEMBL13064098 | 0.68 | SELE (0.35) | — | |
| SCHEMBL8767007 | 0.68 | TP53 (0.32) | JAK2JAK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999031072-A1 | CYCLOHEXYLAMINE ARTHROPODICIDES AND FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-06-24 | — | — | WO | disclosed |