Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 4/20 | 0.32 |
| ▸ | JAK3 | P52333 | 4/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120079 | 0.90 | TP53 (0.33) | TP53LMNAJAK1JAK3JAK2 | |
| SCHEMBL8695199 | 0.74 | JAK3 (0.33) | TP53JAK1JAK3JAK2MEN1 | |
| SCHEMBL8650466 | 0.68 | JAK2 (0.32) | JAK1JAK3JAK2 | |
| SCHEMBL9074942 | 0.68 | MEN1 (0.34) | TP53JAK1JAK3JAK2MEN1 | |
| SCHEMBL9034315 | 0.67 | JAK3 (0.33) | JAK1JAK3JAK2 | |
| SCHEMBL8525079 | 0.64 | MEN1 (0.40) | MEN1KMT2A | |
| SCHEMBL13064098 | 0.64 | SELE (0.35) | RXFP1 | |
| SCHEMBL8490387 | 0.64 | — | — | |
| SCHEMBL28108513 | 0.64 | — | — | |
| SCHEMBL8488727 | 0.63 | KDM4E (0.37) | LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787128-A1 | SUBSTITUTED CYCLOALKYLAMINO AND CYCLOALKOXY HETEROCYCLES, PROCESS FOR PREPARING THE SAME AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1997-08-06 | — | — | EP | disclosed |
| WO-1996011913-A1 | SUBSTITUTED CYCLOALKYLAMINO AND CYCLOALKOXY HETEROCYCLES, PROCESS FOR PREPARING THE SAME AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1996-04-25 | — | — | WO | disclosed |