Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650498 | 0.82 | SRD5A1 (0.48) | — | |
| SCHEMBL8650495 | 0.82 | SRD5A1 (0.48) | — | |
| SCHEMBL8925259 | 0.73 | AR (0.38) | ARKCNH2KMT2A | |
| SCHEMBL8925043 | 0.71 | AR (0.39) | ARKCNH2KMT2A | |
| SCHEMBL9301232 | 0.71 | SRD5A2 (0.54) | — | |
| SCHEMBL8650483 | 0.71 | SRD5A1 (0.35) | KMT2A | |
| SCHEMBL8651043 | 0.71 | SRD5A1 (0.35) | KMT2A | |
| SCHEMBL8926885 | 0.69 | SRD5A1 (0.43) | ARKCNH2KMT2A | |
| SCHEMBL9663769 | 0.68 | SRD5A2 (0.42) | — | |
| SCHEMBL8609868 | 0.68 | CA2 (0.34) | ARKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700291-A4 | 15-SUBSTITUTED 4-AZASTEROIDS | MERCK & CO INC (US) | 1996-07-03 | — | — | EP | claimed |
| EP-0700291-A1 | 15-SUBSTITUTED 4-AZASTEROIDS | MERCK & CO. INC. (US) | 1996-03-13 | — | — | EP | claimed |
| WO-1994020104-A1 | 15-SUBSTITUTED 4-AZASTEROIDS | MERCK & CO, INC. (US) | 1994-09-15 | — | — | WO | claimed |