SCHEMBL8650827

SCHEMBL8650827

CC(OC(=O)N[C@@H](CC(=O)O)C(=O)O)c1ccccc1[N+](=O)[O-]

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.54
TSHR P16473 1/20 0.54
ALDH1A1 P00352 3/20 0.46
MAPT P10636 3/20 0.41
KDM4E B2RXH2 1/20 0.41
CTSL P07711 3/20 0.41
CTSB P07858 3/20 0.41
CYP26A1 O43174 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CASP1 P29466 1/20 0.39
KDM4A O75164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
GAA P10253 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
HTT P42858 1/20 0.38
CASP3 P42574 1/20 0.37
MME P08473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6045038 0.89 FOLH1 (0.47) CYP1A2TSHRALDH1A1CTSLCTSB
SCHEMBL6045035 0.89 FOLH1 (0.47) CYP1A2TSHRALDH1A1CTSLCTSB
SCHEMBL542086 0.82 ALDH1A1 (0.55) CYP1A2TSHRALDH1A1MAPTSMN1; SMN2
SCHEMBL8654472 0.81 ALDH1A1 (0.50) CYP1A2TSHRALDH1A1MAPTL3MBTL1
SCHEMBL18684993 0.80 ALDH1A1 (0.52) CYP1A2TSHRALDH1A1SMN1; SMN2GAA
SCHEMBL29652607 0.78 ALDH1A1 (0.39) CYP1A2TSHRALDH1A1MAPTCTSL
SCHEMBL7718000 0.78 ALDH1A1 (0.52) CYP1A2TSHRALDH1A1MAPTKDM4E
SCHEMBL27889264 0.77 ALDH1A1 (0.56) CYP1A2TSHRALDH1A1MAPTL3MBTL1
SCHEMBL28334172 0.76 ALDH1A1 (0.49) TSHRALDH1A1MAPTKDM4EMEN1
SCHEMBL542087 0.75 ALDH1A1 (0.49) CYP1A2TSHRALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5790627-A Method and apparatus for observing a specimen using an X-ray microscope RESEARCH DEVELOPMENT CORP. (JP) 1998-08-04 US disclosed