SCHEMBL28334172

SCHEMBL28334172

CC(OC(=O)NCCCCC(NC(=O)OC(C)(C)C)C(=O)O)c1ccccc1[N+](=O)[O-]

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.49
TSHR P16473 1/20 0.49
CTSK P43235 4/20 0.42
CXCR3 P49682 1/20 0.42
KLK7 P49862 2/20 0.41
KLK5 Q9Y337 2/20 0.41
MAPT P10636 3/20 0.41
TGM2 P21980 1/20 0.41
PPARG P37231 2/20 0.41
PPARA Q07869 2/20 0.41
NPSR1 Q6W5P4 3/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
POLB P06746 1/20 0.40
KMT2A Q03164 1/20 0.40
SIRT5 Q9NXA8 1/20 0.40
ACE P12821 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
FOLH1 Q04609 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15959933 0.86 ALDH1A1 (0.47) ALDH1A1TSHRKLK7KLK5MAPT
SCHEMBL14353391 0.84 ALDH1A1 (0.40) ALDH1A1TSHRCXCR3KLK7KLK5
SCHEMBL13086269 0.83 MAPT (0.50) ALDH1A1TSHRKLK7KLK5MAPT
SCHEMBL6045038 0.78 FOLH1 (0.47) ALDH1A1TSHRFOLH1
SCHEMBL6045035 0.78 FOLH1 (0.47) ALDH1A1TSHRFOLH1
SCHEMBL9056702 0.78 MGLL (0.51) ALDH1A1MEN1KMT2A
SCHEMBL3619558 0.78 MGLL (0.51) ALDH1A1MEN1KMT2A
SCHEMBL7719022 0.78 KMT2A (0.54) ALDH1A1TSHRMEN1POLBKMT2A
SCHEMBL28684650 0.78 ALDH1A1 (0.49) ALDH1A1TSHRCTSKMAPTPPARG
SCHEMBL28684653 0.78 ALDH1A1 (0.49) ALDH1A1TSHRCTSKMAPTPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108314659-B synthesis and application of epsilon- (1-o-nitrophenyl) ethoxycarbonyl-L-lysine-N-carboxylic anhydride SHANGHAI JIAOTONG UNIVERSITY (CN) 2019-12-10 CN claimed
CN-108314659-B synthesis and application of epsilon- (1-o-nitrophenyl) ethoxycarbonyl-L-lysine-N-carboxylic anhydride SHANGHAI JIAOTONG UNIVERSITY (CN) 2019-12-10 CN disclosed