Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8219841 | 0.78 | GBA1 (0.54) | GBA1DDB1CRBN | |
| SCHEMBL23851449 | 0.78 | TSHR (0.47) | — | |
| SCHEMBL28184637 | 0.78 | — | — | |
| SCHEMBL16289625 | 0.77 | ALDH1A1 (0.40) | GBA1 | |
| SCHEMBL13752557 | 0.77 | S1PR1 (0.38) | — | |
| SCHEMBL16289624 | 0.77 | ALDH1A1 (0.40) | GBA1 | |
| SCHEMBL21051907 | 0.72 | GBA1 (0.46) | GBA1 | |
| SCHEMBL8651297 | 0.72 | GBA1 (0.37) | GBA1 | |
| SCHEMBL27473508 | 0.71 | CCR3 (0.53) | — | |
| SCHEMBL28320965 | 0.71 | HSD11B1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817757-A | AUTOIMMUNE DISORDERS, OLIGOPEPTIDE DERIVATIVES | MERCK & CO., INC. (US) | 1998-10-06 | — | — | US | disclosed |