Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829947 | 0.77 | LMNA (0.67) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL8234055 | 0.77 | HDAC1 (0.79) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL7829459 | 0.77 | LMNA (0.67) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL7831499 | 0.77 | HDAC1 (0.51) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL20545556 | 0.77 | LMNA (0.67) | RECQLMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL12046948 | 0.76 | LMNA (0.68) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL12046962 | 0.74 | LMNA (0.74) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL8047270 | 0.74 | HDAC1 (0.48) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL8047185 | 0.72 | HDAC1 (0.46) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL7382460 | 0.71 | HPGD (0.65) | RECQLMAPTALDH1A1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804601-A | USEFUL FOR TREATING ALZHEIMER'S DISEASE, MULTIPLE SCLEROSIS, BACTERIAL OR VIRAL MENINGITIS, DOWN'S SYNDROME AND PARKINSON'S DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-08 | — | — | US | disclosed |