Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 11/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829657 | 0.87 | SMN1; SMN2 (0.51) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL7832126 | 0.82 | L3MBTL1 (0.48) | MAPTLMNAALOX5 | |
| SCHEMBL5323342 | 0.78 | HDAC1 (0.51) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL8652001 | 0.77 | HDAC1 (0.64) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL7829947 | 0.73 | LMNA (0.67) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL8234055 | 0.73 | HDAC1 (0.79) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL7829459 | 0.73 | LMNA (0.67) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL11514240 | 0.72 | MAPK9 (0.52) | MAPTLMNAALOX5 | |
| SCHEMBL7834650 | 0.72 | HDAC1 (0.71) | HDAC1HDAC2HDAC6HDAC8HDAC3 | |
| SCHEMBL7832947 | 0.72 | HDAC1 (0.48) | HDAC1HDAC2HDAC6HDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737671-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-12 | — | — | EP | disclosed |
| US-5804601-A | USEFUL FOR TREATING ALZHEIMER'S DISEASE, MULTIPLE SCLEROSIS, BACTERIAL OR VIRAL MENINGITIS, DOWN'S SYNDROME AND PARKINSON'S DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-08 | — | — | US | disclosed |
| EP-0737671-A2 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-10-16 | — | — | EP | disclosed |