SCHEMBL8652104

SCHEMBL8652104

CCC(C)CCOC(=O)CCCCCCCCC(=O)OCCC(C)CC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.57
MAPT P10636 1/20 0.49
TSHR P16473 2/20 0.47
DNM1 Q05193 1/20 0.47
CYP3A4 P08684 1/20 0.47
ATM Q13315 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
LMNA P02545 4/20 0.44
ALDH1A1 P00352 2/20 0.43
PAM P19021 2/20 0.43
KDM4E B2RXH2 1/20 0.42
DUSP3 P51452 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PRKCA P17252 1/20 0.40
PRKCE Q02156 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL437997 0.98 DGKA (0.53) DGKAMAPTTSHRDNM1CYP3A4
SCHEMBL28572303 0.94 DGKA (0.48) DGKAMAPTTSHRDNM1CYP3A4
SCHEMBL29306410 0.93 DGKA (0.50) DGKAMAPTTSHRDNM1CYP3A4
SCHEMBL10001375 0.93 DGKA (0.63) DGKAMAPTTSHRDNM1CYP3A4
SCHEMBL844747 0.91 DGKA (0.47) DGKAMAPTTSHRDNM1CYP3A4
SCHEMBL28576540 0.90 ADRA2A (0.45) DGKAMAPTTSHRDNM1CYP3A4
SCHEMBL4287858 0.89 DGKA (0.53) DGKAMAPTTSHRDNM1CYP3A4
SCHEMBL2341571 0.89 DGKA (0.53) DGKAMAPTTSHRDNM1CYP3A4
SCHEMBL18854085 0.89 DGKA (0.53) DGKAMAPTTSHRDNM1CYP3A4
SCHEMBL22567815 0.87 DGKA (0.49) DGKAMAPTTSHRDNM1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250188501-A1 SEMISYNTHETIC ROUTES TO ORGANIC COMPOUNDS AGAIN BIO APS (DK) 2025-06-12 US disclosed
US-12188068-B2 Semisynthetic routes to organic compounds GENOMATICA, INC. (US) 2025-01-07 US disclosed
US-20210310033-A1 SEMISYNTHETIC ROUTES TO ORGANIC COMPOUNDS AGAIN BIO APS (DK) 2021-10-07 US disclosed
US-11008597-B2 Chemo-enzymatic process GENOMATICA, INC. (US) 2021-05-18 US disclosed
EP-3739057-A1 SEMISYNTHETIC ROUTES TO ORGANIC COMPOUNDS Genomatica, Inc. (US) 2020-11-18 EP disclosed
EP-3129492-B1 CHEMO-ENZYMATIC PROCESS FOR THE PREPARATION OF LACTONES AND MACROCYCLIC KETONES GENOMATICA INC (US) 2020-06-03 EP disclosed
EP-3129492-A1 SEMISYNTHETIC ROUTES TO ORGANIC COMPOUNDS REG Life Sciences, LLC (US) 2017-02-15 EP disclosed
US-20170029854-A1 SEMISYNTHETIC ROUTES TO ORGANIC COMPOUNDS REG Life Sciences, LLC (US) 2017-02-02 US disclosed
WO-2015157719-A9 SEMISYNTHETIC ROUTES TO ORGANIC COMPOUNDS REG Life Sciences, LLC (US) 2016-08-04 WO disclosed
WO-2015157719-A1 SEMISYNTHETIC ROUTES TO ORGANIC COMPOUNDS REG Life Sciences, LLC (US) 2015-10-15 WO disclosed
US-5717111-A Process for the continuous preparation of macrocyclic compounds HUELS AKTIENGESELLSCHAFT (DE) 1998-02-10 US disclosed
EP-0260680-B1 Improved process for the production of macrocyclic esters by the depolymerization of polyesters HENKEL CORP (US) 1993-10-27 EP disclosed
EP-0260680-A2 Improved process for the production of macrocyclic esters by the depolymerization of polyesters HENKEL CORPORATION (US) 1988-03-23 EP disclosed
US-4709058-A Process for the production of macrocyclic esters by the depolymerization of polyesters NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1987-11-24 US disclosed
US-4594434-A Macrocyclic compounds NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1986-06-10 US disclosed
US-4499288-A THERMAL DEPOLYMERIZATION OF POLYESTERS; EFFICIENCY NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1985-02-12 US disclosed
US-4393223-A THERMAL DEPOLYMERIZATION OF POLYESTERS EMERY INDUSTRIES, INC. (US) 1983-07-12 US disclosed
US-4331603-A Process for improving the fragrance properties of macrocyclic compounds obtained by thermal depolymerization EMERY INDUSTRIES, INC. (US) 1982-05-25 US disclosed
US-4218379-A Process for the production of macrocyclic esters EMERY INDUSTRIES, INC. (US) 1980-08-19 US disclosed
US-4165321-A Process for the production of heterocyclic compounds HENKEL CORPORATION, A DE CORP. 1979-08-21 US disclosed