Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | CPA1 | P15085 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611291 | 0.77 | SLC1A3 (0.42) | MMESLC1A3SLC1A2CPA1MMP3 | |
| SCHEMBL8612766 | 0.77 | SLC1A3 (0.42) | MMESLC1A3SLC1A2CPA1MMP3 | |
| SCHEMBL8652466 | 0.77 | SLC1A3 (0.42) | MMESLC1A3SLC1A2CPA1MMP3 | |
| SCHEMBL9845297 | 0.77 | SLC1A3 (0.42) | MMESLC1A3SLC1A2CPA1MMP3 | |
| SCHEMBL8654346 | 0.76 | MMP1 (0.32) | MMP3 | |
| SCHEMBL4037754 | 0.74 | MEN1 (0.44) | MMESLC1A3SLC1A2SMN1; SMN2 | |
| SCHEMBL4044696 | 0.74 | MEN1 (0.44) | MMESLC1A3SLC1A2SMN1; SMN2 | |
| SCHEMBL6300523 | 0.73 | ALDH1A1 (0.57) | SMN1; SMN2HRH3 | |
| SCHEMBL17190676 | 0.71 | SMN1; SMN2 (0.53) | SMN1; SMN2CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL5870417 | 0.71 | NOTUM (0.45) | ANPEPMMP3HRH3RNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621867-B1 | NEW ENDOTHELIN ANTAGONISTS AND THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-10-07 | — | — | EP | disclosed |
| US-5538950-A | PEPTIDE DERIVATIVES AS HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| WO-1993010144-A1 | NEW ENDOTHELIN ANTAGONISTS AND THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-27 | — | — | WO | disclosed |