Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 11/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 10/20 | 0.48 |
| ▸ | AR | P10275 | 8/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767831 | 0.95 | PGR (0.53) | PGRNR3C1ARCYP3A4NR3C2 | |
| SCHEMBL30107690 | 0.84 | PGR (0.66) | PGRNR3C1ARCYP3A4NR3C2 | |
| SCHEMBL8768805 | 0.83 | PGR (0.55) | PGRNR3C1ARCYP3A4LMNA | |
| SCHEMBL8767796 | 0.82 | PGR (0.55) | PGRNR3C1ARCYP3A4LMNA | |
| SCHEMBL8652053 | 0.82 | PGR (0.45) | PGRNR3C1ARCYP3A4ABCB11 | |
| SCHEMBL8653263 | 0.82 | PGR (0.45) | PGRNR3C1ARCYP3A4LMNA | |
| SCHEMBL8767943 | 0.81 | PGR (0.51) | PGRNR3C1ARCYP3A4NR3C2 | |
| SCHEMBL8767837 | 0.80 | PGR (0.50) | PGRNR3C1ARCYP3A4NR3C2 | |
| SCHEMBL8768021 | 0.80 | PGR (0.53) | PGRNR3C1ARCYP3A4LMNA | |
| SCHEMBL8536196 | 0.80 | PGR (0.53) | PGRNR3C1ARCYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567472-B1 | D-HOMO-(16-EN)-11 BETA-ARYL-4-ESTRENES, PROCESS FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | SCHERING AG (DE) | 1998-10-07 | — | — | EP | claimed |
| EP-0567472-B1 | D-HOMO-(16-EN)-11 BETA-ARYL-4-ESTRENES, PROCESS FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | SCHERING AG (DE) | 1998-10-07 | — | — | EP | disclosed |
| US-5519027-A | PROGESTERONE ANTAGONIST FOR OXYTOCICS OR PREVENTION OF TERMINATION OF PREGNANCY | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-05-21 | — | — | US | disclosed |