Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.43 |
| ▸ | AR | P10275 | 8/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8652053 | 0.91 | PGR (0.45) | PGRNR3C1ARCYP3A4SERPINA6 | |
| SCHEMBL8652950 | 0.84 | PGR (0.48) | PGRNR3C1ARCYP3A4SERPINA6 | |
| SCHEMBL8652943 | 0.84 | PGR (0.44) | PGRNR3C1ARCYP3A4SERPINA6 | |
| SCHEMBL8767831 | 0.83 | PGR (0.53) | PGRNR3C1ARCYP3A4LMNA | |
| SCHEMBL8652764 | 0.82 | PGR (0.50) | PGRNR3C1ARCYP3A4LMNA | |
| SCHEMBL8652174 | 0.81 | PGR (0.49) | PGRNR3C1ARCYP3A4SERPINA6 | |
| SCHEMBL8650251 | 0.78 | PGR (0.48) | PGRNR3C1ARCYP3A4LMNA | |
| SCHEMBL8653302 | 0.77 | PGR (0.37) | PGRNR3C1ARCYP3A4SERPINA6 | |
| SCHEMBL8767796 | 0.75 | PGR (0.55) | PGRNR3C1ARCYP3A4LMNA | |
| SCHEMBL8768805 | 0.75 | PGR (0.55) | PGRNR3C1ARCYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567472-B1 | D-HOMO-(16-EN)-11 BETA-ARYL-4-ESTRENES, PROCESS FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | SCHERING AG (DE) | 1998-10-07 | — | — | EP | claimed |
| US-5519027-A | PROGESTERONE ANTAGONIST FOR OXYTOCICS OR PREVENTION OF TERMINATION OF PREGNANCY | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-05-21 | — | — | US | claimed |
| EP-0567472-B1 | D-HOMO-(16-EN)-11 BETA-ARYL-4-ESTRENES, PROCESS FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | SCHERING AG (DE) | 1998-10-07 | — | — | EP | disclosed |
| US-5519027-A | PROGESTERONE ANTAGONIST FOR OXYTOCICS OR PREVENTION OF TERMINATION OF PREGNANCY | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-05-21 | — | — | US | disclosed |