Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CCR8 | P51685 | 2/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717987 | 0.90 | CCR3 (0.44) | CCR3HTR7HTR1ADRD2HTR6 | |
| SCHEMBL8483689 | 0.89 | NPSR1 (0.38) | CCR3SLC6A12MEN1KMT2ACNR1 | |
| SCHEMBL8712541 | 0.88 | CCR3 (0.44) | CCR3HTR7HTR1ADRD2HTR6 | |
| SCHEMBL8665520 | 0.86 | CCR3 (0.42) | CCR3HTR7HTR1ADRD2HTR6 | |
| SCHEMBL8665531 | 0.84 | CCR3 (0.41) | CCR3HTR7HTR1ADRD2HTR6 | |
| SCHEMBL8653114 | 0.82 | CCR3 (0.42) | CCR3HTR7HTR1ADRD2HTR6 | |
| SCHEMBL8482587 | 0.79 | CCR3 (0.43) | CCR3HTR7HTR1ADRD2HTR6 | |
| SCHEMBL8485545 | 0.78 | NPSR1 (0.40) | CCR3SLC6A12MEN1KMT2ANPSR1 | |
| SCHEMBL8713186 | 0.78 | DRD2 (0.36) | DRD2MEN1KMT2ACCR8ALDH1A1 | |
| SCHEMBL8482402 | 0.77 | CCR3 (0.35) | CCR3HTR7HTR1ADRD2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712279-A | Inhibitors of microsomal triglyceride transfer protein and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-01-27 | — | — | US | disclosed |