Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.48 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.48 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.48 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | F11 | P03951 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | HMGCR | P04035 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6219613 | 1.00 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL13271930 | 1.00 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL10630111 | 1.00 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL12326365 | 1.00 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL6220333 | 1.00 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL3651596 | 1.00 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL25029339 | 1.00 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL18395710 | 1.00 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL3776331 | 1.00 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL26867534 | 1.00 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10925887-B2 | Steroid saponins with anti-cancer activity | ONCOLOGY RES INTERNATIONAL LIMITED (AU) | 2021-02-23 | — | — | US | disclosed |
| EP-2852607-B1 | SYNTHESIS OF STEROID SAPONINS | ONCOLOGY RES INTERNATIONAL LIMITED (AU) | 2018-10-24 | — | — | EP | disclosed |
| EP-3066108-A1 | 4-{4-[(1 E)-4-(2,9-DIAZASPIRO[5.5]UNDEC-2-YL)BUT-1 -EN-1 -YL]-2-METHYLBENZYL}-5-(PROPAN-2-YL)-1 H-PYRAZOL-3-YL BETA-D- GLUCOPYRANOSIDE ACETATE | Eli Lilly and Company (US) | 2016-09-14 | — | — | EP | disclosed |
| WO-2015069541-A1 | 4-{4-[(1 E)-4-(2,9-DIAZASPIRO[5.5]UNDEC-2-YL)BUT-1 -EN-1 -YL]-2-METHYLBENZYL}-5-(PROPAN-2-YL)-1 H-PYRAZOL-3-YL BETA-D- GLUCOPYRANOSIDE ACETATE | ELI LILLY AND COMPANY (US) | 2015-05-14 | — | — | WO | disclosed |
| US-20150105543-A1 | SYNTHESIS | ONCOLOGY RESEARCH INTERNATIONAL LIMITED (AU) | 2015-04-16 | — | — | US | disclosed |
| US-5756712-A | REPLACING THE ETHER OXYGEN LINKAGE OF OLIGOSACCHARIDES WITH A PEPTIDE LINK, WHERE THE NITROGEN ATOM IS LINKED TO THE ANOMERIC CARBON ATOM OF THE SUGAR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0553297-B1 | PROCESS FOR THE PREPARATION OF GLYCOSYL PHOSPHATE TRIESTERS | DU PONT (US) | 1995-01-25 | — | — | EP | disclosed |
| US-5288859-A | Reacting metal azide with glycosyl phosphate triester | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-02-22 | — | — | US | disclosed |
| WO-1992009612-A1 | PROCESS FOR THE PREPARATION OF GLYCOSYL PHOSPHATE TRIESTERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-06-11 | — | — | WO | disclosed |
| US-5095123-A | Phosphorylation | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-10 | — | — | US | disclosed |
| US-4792615-A | HYDROLYSIS OF A-DIHYDROPOLYPRENYL DICHLOROPHOSPHATE WITH ALKALI OR ALKALINE EARTH METAL HYDROXIDE; POLYISOPRENE | NAKAGAWA NAOSHI (JP) | 1988-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10925887-B2 | Steroid saponins with anti-cancer activity | CD4, NFATC1, HSD11B1 | USP2 4364/4885POLB 3455/4885MEN1 3905/4885 |
| US-20150105543-A1 | SYNTHESIS | CYP17A1, CYP21A2, CYP11A1 | USP2 2499/4885POLB 4639/4885MEN1 1047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.